Which gland is responsible for producing cortisol, according to the endocrine structures listed?

• A. Pituitary gland
• B. Adrenal glands
• C. Thyroid gland
• D. Pancreas

Answer: (B)

Cortisol is produced by the adrenal glands, specifically in the adrenal cortex. The pituitary gland signals this production by releasing ACTH in response to hypothalamic cues, but the actual cortisol synthesis occurs in the adrenal cortex itself. The thyroid gland and pancreas do not produce cortisol; the thyroid makes thyroid hormones, and the pancreas makes insulin and glucagon.