Which term describes a degenerative brain disease that occurs gradually?

• A. Guillain-Barre Syndrome
• B. Meningitis
• C. ALS
• D. Alzheimer's Disease

Answer: (D)

A gradual, progressive decline in cognitive function due to brain degeneration describes Alzheimer's disease. It starts with subtle memory lapses and gradually worsens, affecting thinking, language, and daily functioning as brain cells deteriorate and brain plaques and tangles accumulate. The other conditions don’t fit this pattern: Guillain-Barre syndrome is an acute, rapid-onset disorder of the peripheral nerves; meningitis is an acute infection causing inflammation of the meninges; ALS is a progressive motor neuron disease that primarily affects movement rather than cognitive decline. So the description points to Alzheimer's disease.